Prospective Clients

Prospective Clients for Structure Based Drug Design and Computational Chemistry Services

Companies that have identified their drug(protein) targets, we can assist optimization in every stage from early discovery to preclinical developement

  • To improve lead compound potency
    - Target validation
    - Boost potency
    - Establish SAR
    - Generate back up compounds for clinic trial candidate
    - Optimize selectivity
  • To search drug-like properties
    - Alter PK property and half life
    - Improve ADME
    - Reduce toxicity
  • To seek outside fresh ideas to move internal project forward
  • - Provide strategic insight through structure modeling for small molecule project
    - Assist selection of clinical compound (go/no go decision)
    - Retrospectively to assess results of project

Rebexsess computational/modeling services with Known Protein Structure is very cost-effective for lead optimization, promotion of SAR and drug-like properties. Please find out if the structure of your drug target is available on the public domain-Protein Data Bank.

If your protein target structure unknow, please contact us for further assistance.

The advantages of Rebexsess SBDD service are:

  • accelerating the process of chemistry discovery
  • obtaining a unique insight into SAR
  • pointing direction for improving potency and bioavailability of lead molecules
  • delivering real results without expensive in-house SBDD and computational chemistry infrastructures

Medicinal Chemistry Service for Emerging/Startup Companies

These innovative therapeutic emerging companies that have developed novel biological screening technology, intend to raise funding and get quick results with limited budget:

  • Initiating chemistry discovery projects without a costly Medicinal Chemistry group
  • Proof of concept of client's technology through small molecule chemistry