ADVANTAGE in Computational Chemistry Services and Consulting:
Rebexsess offers unique and outstanding computational chemistry consulting and service. Our computational chemists are professionally trained in Organic/Medicinal Chemistry with extensive hands-on experience of computational/modeling and practical approaches, which designs accessible small molecules and targeted modified proteins/enzymes.
Service Aspects for Structure Based Drug Design
Computational analysis of docked pose
Homology Modeling for related drug targets
Development of SAR in context of receptor
Use of structure to improve potency and selectivity
Use of structure to improve drug-like properties
Computational docking of small molecules to proteins
Virtual screening of small molecule libraries
Service Aspects for Structure Based Enzyme Engineering
Development of models for Enzyme Catalysis
Homology Modeling for related drug targets
Rebexsess Core Technology: Solving the “numbers problem” in Directed Evolution
Homology Modeling for enzymatic engineering
Development of SFR(structure function relationship) in context of enzyme
Design of specific enzyme murations
Design of screening libraries for Directed Evolution